The Angels and Athletics meet again in this AL West showdown on May 22. With both teams dealing with injuries and inconsistent play, this matchup provides a valuable betting opportunity. Let’s dive into my Angels vs Athletics prediction and break down the trends, odds, and best bets from the Rithmm model.

Preview of Angels vs Athletics Prediction

The Angels vs Athletics game is scheduled for 3:35 PM ET on May 22 at Sutter Health Park. The Angels are riding a hot ATS streak, while the Athletics continue to underwhelm, especially at home. My Angels vs Athletics prediction indicates a strong value on the underdog—yet again.

Injury Report for Angels vs Athletics

Both teams are heavily impacted by injuries, particularly in their pitching and infield depth.

Angels Injury Report:

• Garrett McDaniels (D15 – Bicep)
• Yusei Kikuchi (Day-to-Day – Ankle)
• Anthony Rendon (D60 – Hip)
• Benjamin Joyce (D60 – Shoulder)
• Michael Trout (D10 – Knee)
• Gustavo Campero (D10 – Ankle)
• Patrick Sandoval (D60 – Elbow)
• José Fermin (D15 – Elbow)

Athletics Injury Report:

• José Leclerc (D60 – Shoulder)
• Kenneth Waldichuk (D60 – Elbow)
• John Ginn (D15 – Quadriceps)
• Zachary Gelof (D10 – Hand)
• Luis Medina (D60 – Elbow)
• Timothy McFarland (D15 – Groin)
• Jacob Wilson (Day-to-Day – Forearm)
• Brady Basso (D60 – Shoulder)

Who is Favored to Win Angels vs Athletics?

Oddsmakers are showing caution, with the Angels +1.5 line at -171 odds and a 67.5% win probability according to the Rithmm model. Despite the injuries, the Angels continue to show resilience, especially on the road, making this Angels vs Athletics pick attractive for run line bettors.

Angels vs Athletics History

Let’s take a look at recent Angels vs Athletics trends:

• Angels are 5-0 ATS overall
• Angels are 5-0 ATS as away underdogs
• Athletics are 2-3 ATS overall
• Athletics are 0-3 ATS at home and as favorites

These Angels vs Athletics trends show consistent underperformance from Oakland and a stellar ATS run from the Angels.

How Many Times Has Angels Beat Athletics?

The Angels have covered the run line in all five of their last five games, including against stronger teams. The Athletics have struggled both at home and when favored, giving the Angels an edge in this matchup.

Model Used For My Angels vs Athletics Best Bet Prediction

My Rithmm Pre-Built MLB Model analyzes this game using:

• Current ATS trends
• Injury depth impact
• Matchup splits
• Team scoring projections

It predicts a 5.0 to 4.0 Angels win, projecting a solid run-line buffer.

What Chance Does Angels Have of Beating Athletics?

According to the model, the Angels have a 67.5% probability of covering the +1.5 spread, making them a strong play in this Angels vs Athletics prediction despite roster limitations.

Best Odds for Angels vs Athletics

Here’s where to get the best Angels vs Athletics Best Odds:

• FanDuel: +1.5 (-164) – Best value
• PointsBet, DraftKings, William Hill: +1.5 (-169 to -170)
• MGM: +1.5 (-190)

FanDuel offers the best line for this Angels vs Athletics pick, giving bettors the edge on value.

My Pick for Angels vs Athletics

Based on the data, my Angels vs Athletics pick is Angels +1.5 (-164). With a perfect ATS record in the last five games and favorable matchup analytics, the Angels remain a top model-backed bet even as underdogs.

Explore More Angels vs Athletics Predictions

Looking for more AI-powered predictions? Check out:

• AI Sports Betting insights for smarter decision-making.
• MLB AI Sports Predictions for advanced game insights.
• Computer MLB Picks for expert computer-driven predictions.
• MLB PrizePicks for AI PrizePick predictions.
• AI MLB Player Props for deeper in-game data

This AI sports betting analysis is just a glimpse of what you can expect when using Rithmm. Whether you’re looking to refine your betting strategy or want to explore in-depth data trends, Rithmm's AI tools for sports betting has all you need. Don't miss out on making more informed decisions—download the Rithmm app today for full access to our AI baseball predictions, MLB Computer Picks, AI Player Props, and custom sports betting models.